ncRNA name | ITGA5 shRNA |
ncRNA Category | shRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | human choroidal endothelial cells |
Methods | shRNA knockdown, tube formation assay, transwell assay, MTS cell proliferation assay, Western blot |
Expression pattern | associated |
Functional description | Integrin α5 knockdown by shRNA inhibits endothelial cell migration, tube formation, and proliferation. |
PubMed ID | 27089240 |
Year | 2016 |
Title | Joint Antiangiogenic Effect of ATN-161 and Anti-VEGF Antibody in a Rat Model of Early Wet Age-Related Macular Degeneration. |
Drug-related ncRNA | NA |
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